Is ACTN3 R577X Genotype Associated with a Preference in Type of Exercise Such as Sprint or Endurance?
نویسندگان
چکیده
منابع مشابه
ACTN3 (R577X) genotype is associated with fiber type distribution.
alpha-Actinin-3 is a Z-disc structural protein found only in type II muscle fibers. The X allele of the R577X polymorphism in the ACTN3 gene results in a premature stop codon and alpha-actinin-3 deficiency in XX homozygotes. Associations between the R577X polymorphism and the muscle-power performance of elite athletes have been described earlier. About 45% of the fiber type proportions are dete...
متن کاملThe ACTN3 R577X variant in sprint and strength performance
PURPOSE The aim of this study is to examine the association between the distribution of ACTN3 genotypes and alleles in power, speed, and strength-oriented athletics. METHODS ACTN3 genotyping was carried out for a total of 975 Korean participants: top-level sprinters (n = 58), top-level strength athletes (n = 63), and healthy controls (n = 854). RESULTS Genetic associations were evaluated by...
متن کاملInteraction Between ACE I/D and ACTN3 R557X Polymorphisms in Polish Competitive Swimmers
We hypothesized that the ACE ID / ACTN3 R577X genotype combination was associated with sprint and endurance performance. Therefore, the purpose of the present study was to determine the interaction between both ACE ID and ACTN3 R577X polymorphisms and sprint and endurance performance in swimmers. Genomic DNA was extracted from oral epithelial cells using GenElute Mammalian Genomic DNA Miniprep ...
متن کاملIs the interaction between HIF1A P582S and ACTN3 R577X determinant for power/sprint performance?
Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that regulates gene expression in response to hypoxia and has been associated with athletic performance. The aims of this study were (1) to determine the frequency distribution of HIF1A Pro582Ser (rs11549465) polymorphism among 155 Israeli athletes (sprinters and endurance athletes) and 240 healthy controls and (2) to analyze the infl...
متن کاملACTN3 R577X polymorphism is not associated with team sport athletic status in Italians.
BACKGROUND The ACTN3 gene may influence performance in team sports, in which sprint action and high-speed movements, regulated by the anaerobic energy system, are crucial to the ultimate success of a match. The aim of this study was to determine the association between the ACTN3 R577X (rs1815739) polymorphism and elite team sport athletic status in Italian male athletes. METHODS We compared t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Advances in Physical Education
سال: 2021
ISSN: 2164-0386,2164-0408
DOI: 10.4236/ape.2021.112022